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Probe Designs
NeuroNexus Technologies' unique technologies enable fabrication of probes of any 2-dimensional shapes.  NeuroNexus  probe catalog includes a set of more commonly requested probe designs.

Currently, we offer probes with 2D electrode counts of 16, 32, or 64 contacts in one single probe. These probes vary in a few design parameters: number of shanks (spanning the cortical columns), length of shank (spanning different cortical layers), electrode site area, electrode spacing, and tetrode configuration.

All probes are mounted and electrically connected to PC boards using ultrasonic bonding. Exposed connections are stabilized and insulated with silicone and/or epoxy. The  I/O pins on the PC board mate directly to standard integrated circuit DIP sockets or commercial  connectors, permitting easy handling and connection.  See Probe Packages for more information.

There are currently two types of probe designs available:


A-Style Probe Design

A-Style probe design is the most versatile and has the most number of designs. 

A-Style probes were originally referred to as "acute" probes.  The word "acute" was misleading because A-Style probes can also be implanted chronically with appropriate probe packages.  Probe model numbers starting with 'a' are A-style probes.

By default, A-Style Probes are packaged in  A-Series Packages, which is appropriate for acute use with normal prep. A-Style Probes can also be combined other probe packages for more advanced and specialized applications.   

  
C-Style Probe Design

The primary difference between A-Style  and C-Style Probes is that C-Style Probes have an integrated flexible silicon ribbon cable (a 5um thin, narrow cable as pictured in the topper middle part of the photo). This  cable allows the C-Style Probes to be inserted into neural tissue and “float” with the brain, while a percutaneous connector can be mounted on a bone screw around the craniotomy.  The implantable portion of both A-Style and C-Style probes have the same feature spaces such as: geometric shape, thickness, and insulation material.

C-Style Probes are recommended for most chronic experiments.  Users with the following conditions might consider A-Style Probes with customized packages for chronic experiments:

  • Chronic implants for small animal models (such as mice).
  • Users who prefer not to handle silicon probes by hand.
  • Procedures require the use of micromanipulator for implantation.
  • Experiments require implants to be moved over the course of experiment.
New users, be sure to check out Chronic Startup Kit and Supplementary Kit, which are designed to assist users on the handling of C-Style Probes.
  
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