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Electrode Arrays

Optogenetics

NeuroNexus optoelectrodes enable concurrent optogenetic stimulation and high-resolution electrophysiology.

Operators
  • A powerful tool – Optical fibers are laminated onto silicon probes to create an optoelectrode. Utilize a single fiber, or configure multiple fibers on a single probe (one fiber per electrode shank) to activate different opsins or target different brain areas.
  • Many options:
    • Utilize any electrode array design
    • Select from multiple fiber types (and specify their termination locations on each shank) to create your ideal optoelectrode
  • Minimal tissue damage – Our smallest fiber option measures just 62.5 µm outer diameter
  • Controlled artifact – NeuroNexus optoelectrodes are engineered for minimal photoelectric artifacts

O-Series packages come with attached optical fiber(s). All are configured so that the fiber extends as straight up from the shank(s) as possible, moving the headstage connector portion off to the side.

OH-series packages must be ordered with an oDrive.

Visit the optogenetic variant of SiNAPS packages here.

Please note all NeuroNexus optoelectrode packages should have ‘LP’ (low profile/ferrule connection) to distinguish them from older devices built with the discontinued NNC ferrule connector.

For information regarding connector package specifications, please visit product documentation here.

 

Flat Fiber Properties

Ferrule Size

1.25 mm

Length

Tolerance ± 50 µm

Fiber Tip Profile

Flat

Note

Any internal reference site or electrode sites covered by the optical fiber will be non-functional.

Inner Diameter/Outer Diameter

Numerical Aperture

50 µm/62.5 µm

0.22 NA (etched)*

105 µm/125 µm

0.22 NA (standard)

105 µm/125 µm

0.66 NA (Plexon patch cords)

200 µm/220 µm

0.22 NA

Lambda Fiber

Lambda Fiber Stubs (NA, ID, OD)

Active Length

0.22 NA/105 µm/125µm

0.5, 1.0, 1.5 mm

0.39 NA/200 µm/225µm

0.5, 1.0, 1.5, 2.0, 2.5 mm

0.66 NA/200 µm/230µm

0.5, 1.0, 1.5, 2.0, 2.5 mm

Implant Length

0-20 mm

*Please note that we previously offered 50/70 µm, 0.22 NA fibers. The 50/62.5 µm, 0.22 NA fibers have significantly better light transmission so we default to this selection for 50 µm core fiber requests.

Single-Fiber

Standard or 4-channel microelectrode arrays can be configured as an Optoelectrode. An optical fiber is placed on the recording side of the shank, and terminates at your desired location above the proximal recording site, to 50 µm accuracy. Multi-shank microelectrode arrays can be configured as optoelectrodes, but have limitations on fiber placement. Contact us for more information.

Multi-Fiber

Up to one fiber per shank can be configured. Because of the physical limitations of optical fibers and NeuroNexus microelectrode arrays, there are some design constraints.

Optogenetics Accessories

Optogenetics-enabled Microdrives

Light Sources and Instrumentation

 

 

Optoelectrode maps are identical to the non-Optoelectrode versions of the same probe. For example, the maps for OA32LP and A32 probes are the same. Note that OA32LP_v2 and OA64LP_v2 mapping is unique.