Our flagship silicon probes are a reliable and reproducible substitute for wire bundles. Suitable for acute and chronic use, they interface with cortex or small animal deep brain structures, as well as the spinal cord, heart, or other tissues. Choose from the world’s largest catalog of probe designs to find the one best suited to your target region and analyses, then select the appropriate connector package to order a completely assembled probe.

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Consistent results – NeuroNexus microelectrodes are produced with reliable mechanical, and geometric characteristics. This means fewer variables for you to manage.
A Toolbox of designs – We offer a huge variety of electrode array designs for different applications and/or brain structures. Think of it as selecting the right tool for your task – and if you need a custom design, we can make it for you.
Acute and chronic – Probes can be used successfully in both acute and chronic applications.
Connect to any system – Each microelectrode array is matched with a connector package to connect to a headstage. NeuroNexus collaborates with system manufacturers to ensure our probes connect seamlessly.

“Since NeuroNexus began fabricating probes with high reliability and reasonable costs, we virtually stopped using wire electrodes and monitor electrical activity with silicon probes. It is a one-way process: once one begins to record with silicon probes, he/she never goes back to wires.”

Dr. György Buzsáki

New York University

Linear electrode arrays are the foundation for multichannel recordings. The laminar design allows for a longer area of coverage than a single tip site, and either facilitates or replaces the need for passage-type experiments. Linear electrode arrays fit the widest range of applications.
Edge sites are similar to the Linear layout, but electrode sites are strategically positioned at the edge of the substrate.
Tetrode is an arrangement of four electrode sites placed close together, allowing for high-quality cell discrimination in recordings.
Polytrode electrode site layouts come in variations, e.g., Poly2 (two columns of sites, shown left), Poly3 (three columns of sites), etc. They have a mix of linear and tetrode beneﬁts, with sites close enough together to allow a degree of multiple representations across different sites while sampling a larger space.
Multi-shank electrode arrays provide a two-dimensional representation of the brain. By controlling shank and site spacing, a more detailed understanding can be obtained of a larger space in the brain. Some multi-shank designs incorporate tetrode and polytrode site arrangements.

A-Series (acute) is the standard probe package for acute experiments. The package is easy to handle and can be used with standard stereotaxic frames and multichannel recording headstages.
CM-Series (Omnetics) are one type of package that allows microelectrode arrays to be implanted chronically. The small form factor and lightweight Omnetics connector permit the CM-series package to be used for chronic implantation.
SEA-Series (Plexon HST/64 and 128) is a compact package with a Samtec connector interface for chronic recordings
H-Series (flexible) is a hybrid package introducing a flexible ribbon between the silicon probe and connector PCB to allow connector stand-off or use with a microdrive.
X-Series (NEW!) mate directly with X-Headstages. See X-Series Probes.
Z-Series (TDT ZIF) are designed for minimal connection force impact exerted on the animal. They use TDT’s patented ZIFCLIP^TM technology.
MR-Series (MRI) are Omnetics connector-based packages that are MR-compatible.
D-Series (drug delivery) come with attached fluidic channels for drug delivery, and chemical sampling. See Combined Drug Delivery and Electrophysiology
O-Series (optogenetics) come with attached optical fiber(s) to enable optical stimulation combined with precise neural recording in optogenetics experiments. See Optogenetics

For information regarding connector package specifications, please visit product documentation here.

Electrode Site Material

Iridium (standard), Platinum (custom), Gold (custom)

Electrode Thickness

15 µm or 50 µm (varies by design)

Electrode Length

2 – 15 mm (varies by design, contact us for special needs)

Channel Count

4, 8, 16, 32, 64, 128, 256 (varies by design)

Each probe consists of two parts: an electrode array and a package. You must specify both to place an order.

First, using our electrode array design catalog, select an electrode array design that meets your experimental needs. Consider how the array design matches your target depth and shape, and if you require a particular site layout(e.g. tetrode or polytrode for cell discrimination, linear for laminar coverage).
Secondly, select a probe package that matches your headstage and/or recording system.

Microelectrode Array Design Catalog

Probe Usage Tips

Probe Site Mapping: 4-ch package; 16-ch package; 32-ch package; 64-ch package; Legacy designs

Surgical Guide for Acute Penetrating Arrays

Surgical Guide for Chronic Penetrating Arrays

Small Animal

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