Up to 15 mm Depth Microelectrodes

 

penetrating image

Standard probes are suitable for implanting into cortex or deep brain structures, as well as for interfacing with spinal cord, heart or other tissues. Our technology offers a comprehensive design space capable of covering a 2-dimensional plane where electrode sites can be tailored to span cortical layers, or cortical columns of the brain. Alternatively, a volume of tissue can be covered by combining multiple 2-dimensional arrays. NeuroNexus offers a wide variety of penetrating probe designs to meet each and every unique requirement.


"Since NeuroNexus began fabricating probes with high reliability and reasonable costs, we virtually stopped using wire electrodes and monitor electrical activity with silicon probes. It is a one-way process: once one begins to record with silicon probes, he/she never goes back to wires."

Dr. György Buzsáki

New York University


Key Features:

  • Consistent results – NeuroNexus microelectrodes are produced with reliable mechanical, and geometric characteristics. This means fewer variables for you to manage.
  • A Toolbox of designs – We offer a huge variety of electrode array designs for different applications and/or brain structures. Think of it as selecting the right tool for your task – and if you need a custom design, we can make it for you.
  • Acute and chronic – Probes can be used successfully in both acute and chronic applications.
  • Connect to any system – Each microelectrode array is matched with a connector package to connect to a headstage. NeuroNexus collaborates with system manufacturers to ensure our probes connect seamlessly.

Site Layout:

Below are examples of the different types of electrode array tips.

  • Linear electrode arrays are the foundation for multi-channel recordings. The laminar design allows for a longer area of coverage than a single tip site, and either facilitates or replaces the need for passage-type experiments. Linear electrode arrays fi t the widest range of applications.
  • Edge sites are similar to the Linear layout, but electrode sites are strategically positioned at the edge of the substrate.
  • Tetrode is an arrangement of four electrode sites placed close together, allowing for high-quality cell discrimination in recordings.
  • Polytrode electrode site layouts come in two variations: Poly2 (two columns of sites, shown left), or Poly3 (three columns of sites). They have a mix of linear and tetrode benefi ts, with sites close enough together to allow a degree of multiple representation across different sites, while sampling a larger space.
  • Multi-shank electrode arrays provide a two-dimensional representation of the brain. By controlling shank and site spacing, a more detailed understanding can be obtained of a larger space in the brain. Some multi-shank designs incorporate tetrode and polytrode site arrangements.

Connector Package:

  • A-Series is the standard probe package for acute experiments. The package is easy to handle and can be used with standard streotactic frames and multichannel recording headstages.
  • CM-Series are one type of package that allow microelectrode arrays to be implanted chronically. The small form factor and light weight permits the CM-series package to be used for chronic implantation.
  • C-Series differs from teh CM-Series in connector orientation and size.
  • H-Series is the standard interface package for our polymer based components. A microelectrode array can be combined with a flexible cable using this package.
  • Z-Series are designed for minimal connection force impact exerted on the animal. They use TDT's patented ZIFCLIPTM technology.
  • MR-Series are Omnetics connecteor-based packages that are MR compatible.
  • D-Series come with attached fluidic channels for drug delivery, chemical sampling.
  • O-Series enables optical stimulation combined with precise neural recording in optogenetics experiments.