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Multi-Probe Micromanipulator (MPM) System
Instrumentation

Multi-Probe Micromanipulator (MPM) System

Maximize productivity and master multiple simultaneous recordings with automated probe positioning, MPM, the only micromanipulator designed specifically for positioning the newest silicon probes used in acute recordings.

Operators
  • Get creative with your experiments – Isolate neurons with one probe, record LFPs with a second probe, and stimulate with a third, all while recording mapped signals with the SmartBox Pro data acquisition system. The sky’s the limit!
  • Easily control 5 or more probes – Each probe micropositioner enables 3 axes of motion, all controlled by a single computer application.
  • Gross manual + Fine automated control – Four-axis arms enable quick setup, and three-axis automated micromanipulators adjust probe position with sub-micrometer precision.
  • Flexible device compatibility – Use any combination of probes, tetrodes, optical fibers, and waveguides to take your experiment to the next level.

Multi-Probe Micromanipulator (MPM) System

Pathfinder Software: Planning, Simulation, Execution

MPM Pathfinder Software with Virtual Coordinate System (VCS) simplifies planning, simulation, and execution. Leverage Pathfinder’s simulation mode to efficiently strategize and visualize probe positions and approach angles. With this feature, you can check for any potential interference and effectively practice insertions before actual implementation. This ensures a more informed and precise execution of your experiments.

The integration of the Radiens Allego with MPM System Pathfinder Software empowers users to observe both physiology and anatomy simultaneously during probe insertion and neural recording. This integration facilitates the simulation, planning, execution, debugging, and repetition of experiments with enhanced ease and precision.

As the insertion progresses, relay the probe coordinates to Radiens Allego to enable the real-time display of brain region activity and channel depth. This dynamic visualization provides valuable insights into the ongoing neural response throughout the insertion process.

 

 

MPM Properties

Travel Range

15 mm / axis

Payload

100 g (recommended) / 200 g (maximum)

Speed

4 mm/s

Resolution

0.5 µm

Bi-Directional Repeatability

<5 µm

Accuracy

<20 µm

Dimensions

32 mm x 32 mm x 11 mm with each embedded controller

  • NeuroNexus Acute Probes: A16, A32, and A64 packages – with adaptors to common Omnetics headstages (e.g., Intan, OpenEphys) are used with MPM Probe Mount-2M.
  • SiNAPS Pixel Probes: Adapters included with SiNAPS probe, choose IST-2mm rod.
  • NeuroNexus Smart Probes: Choose MPM Probe Mount-9 for NeuroNexus I128 or S128 probes, designed for use with Intan 128-channel headstage modules.
  • Neuropixels Probes: Choose MPM Probe Mount-1AS
  • Syringe Holder: Choose MPM Syringe Mount-8

Items needed for each MPM system:

  • MPM-System Kit: Includes mechanical hardware, instructions, USB hub, USB cables, and MPM software.
  • MPM-Ring-72-DEG: Mounting ring for 72-degree section. Minimum required: ONE for 1-2 probes, TWO for 3-4 probes, THREE for 5 probes.
  • MPM-Platform (Optional): The platform for mounting MPM rings and manipulators in an inverted configuration.
  • MPM-Joystick (Optional): Joystick with USB connection to operate MPM software.

Items needed for each probe:

  • MPM-4 DOF ARM-X: MPM four-degree-of-freedom manual positioner (specify upright or inverted configuration)
  • M3-LS-3.4-15-XYZ-MPM-X: Three-axis motorized micromanipulator. Includes: (3) M3-LS-3.4-15 Linear Smart Stages assembled into XYZ configuration, (1) M3-USB-3:1 Adapter (Specify upright or inverted configuration)
  • MPM-Probe Mount-X: Mounting bracket and kit for specific probes. Contact us for options.