Data Acquisition

SmartBox Pro™

The latest Smart data acquisition box from NeuroNexus: 1024 channels in a portable format to simplify complex experiments, powered by the Radiens™ software suite.

If you are interested in stimulation or switchable experiments, check out the XDAQ™ systems.


  • High-performance
    Up to 1024 lightning-fast channels for real-time processing of spikes, field potentials, and other physiological signals. Cutting-edge Allego software allows for a customizable workspace to save time and acquire rich datasets, every time.
  • Intuitive “Probe-centric” User Interface
    Built-in probe maps at your fingertips. Instant and precise spatiotemporal relationships among signals. Simply connect a NeuroNexus probe and headstage amplifier to start focusing on your high-impact science in seconds!
  • Affordable, Easy to Integrate, Open Neuroscience-friendly
    Low-cost, easy-to-use, complete solution with the functionality of an expensive, rack-mounted system. A simple yet powerful system that will grow with your lab.
  • Impedance Measurement
    Monitor the site impedances of your probes.
  • Seamless Probe Integration
    Plug-and-play compatibility with all NeuroNexus electrodes, including fully integrated probe maps.
  • Flexible Post-Processing and Data Analysis
    We save raw data alongside meta-data in popular, non-proprietary file formats for straightforward integration into existing data analysis workflows. Matlab, python, and R friendly.
  • Portable
    The small hardware footprint and laptop compatibility make the system highly portable, including for use in intra-operative environments.
  • Cross-Platform Compatibility
    USB 3.0 plug-and-play compatible that runs on laptops and workstations (Windows, Mac, and Linux compatible)

Acquisition Channel Count

Up to 1024

A/D Resolution

16-bit, 0.15 μV

Sampling Rates

1—30 k Samples/s per channel

Peripheral Output

2 Analog, BNC (± 3.3 V)

2 Digital, BNC (0-5 V TTL)

Peripheral Input

2 Analog, BNC (+/-5 V)

2 Digital, BNC (0-5 V TTL)

Audio Monitoring

1 stereo line out (3.5 mm), user selectable

Cutoff Frequency


Low: 0.1 – 500 Hz

High: 100 Hz- 20 kHz

Low Input-referred Noise

2.4 μV RMS typical

Smallest Detectable Signal

15 μV


7” x 5” x 1.5” (LxWxH)



3 lbs

Included with every SmartBox Pro:

  • SmartBox Pro box
  • SmartBox Pro USB Cable
  • SmartBox Pro AC Adapter
  • Power Cord
  • 2 BNC to BNC
  • 2 BNC to Alligator
  • 1 Blue Banana to Banana Cable
  • 1 Black Banana to Banana Cable

Perpetual right to use Radiens Allego required to control the SmartBox Pro


Recommended products to order with the SmartBox Pro:

SmartLink headstage(s)

SmartLink cable(s)

X-Series headstage (X3R32, X3R64, X6R128)


Activus probes

Check SmartBox Pro Knowledge Base for a brief overview of the SmartBox Pro system and some of its basic functions.