Joshua M. Brenner and Riccardo Beltramo et al. from Massimo Scanziani’s lab at UCSF used three NeuroNexus acute probe designs (A1x32-Edge-5mm-20-177-A32, A4x2-tet-5mm-150-200-121-A32, and A1x16-5mm-25-177-A16) plus optoelectrodes (A1x16-5mm-25-177-OA16LP) to record throughout the lateral visual pathway in awake, head-fixed mice. Simultaneous single-unit recordings with optogenetic silencing of specific neurons in the superior colliculus (SC) were one key part of their study to identify and characterize the pathway from SC to visual cortices via the pulvinar.
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For in vivo ephys experiments performed with the NeuroNexus SmartBox Pro™ and Radiens™ Allego software, Marine Tessier et al. with Claudio Rivera’s groups at Aix Marseille University and the University of Helsinki used NeuroNexus A1x16-3mm-100-177-A16 probes. They recorded LFP and single-units of wide-spiking and narrow-spiking neurons in the hippocampus of mice subjected to controlled cortical impact (CCI) as a model of brain injury to study non-neuronal targets of bumetanide.
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A1x16-5mm-100-177-CM16LP probes from NeuroNexus spanned layers II/III to V/VI of the barrel field in rat somatosensory cortex (S1BF) to allow layer-specific analyses including CSD. Xunda Wang et al. with Ed X. Wu’s lab at the University of Hong Kong optogenetically-induced spindle activities from ventral posteromedial thalamus (VPM) and used fMRI together with electrophysiology to precisely probe and characterize the temporal and spatial properties of the spindle activities throughout the brain.
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