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Science Updates

Testing micro-coils for magnetic stimulation

NeuroNexus E16-500-5-200-H16 ECoG grids recorded visually-evoked potentials as well as responses to magnetic stimulation in mouse visual cortex. The recordings were done in Shelley Fried’s lab at Massachusetts General Hospital and used to validate new MEMS micro-coils described in Xiyuan Liu et al.

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Testing micro-coils for magnetic stimulation
Science Updates

Neural mechanisms of altered sensorimotor processing in ASD and others

Alice Zheng et al with Brian Allman and Susanne Schmid at the University of Western Ontario used NeuroNexus A1x32-5mm-25-177-A32 linear probes to record from the pontine reticular nucleus (PnC) and A1x32-Poly2-5mm-50s-177-A32 polytrodes to record from the pedunculopontine tegmentum (PPTg) in Cntnap2 knockout mice, a model for neurodevelopmental disorders. Their work in IBRO Neuroscience investigates changes in auditory processing not apparent from an ABR test.

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Neural mechanisms of altered sensorimotor processing in ASD and others
Science Updates

V1 contextual responses depend on perceptual organization

Lisa Kirchberger et al. with Pieter Roelfsema’s group at the Netherlands Institute for Neuroscience used NeuroNexus A1x32-5mm-25-177-A32 acute probes localized by current source density analysis (CSD) in primary visual cortex (V1) of awake behaving mice. The laminar probe spanned the layers of V1 and recorded multi-unit activity, MUA, as well as individual units for receptive field (RF) characterization. Their results in Science Advances address cortical responses to contextual information outside the RF, which were most driven by disinhibitory VIP neurons and play a role in figure perception. 

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V1 contextual responses depend on perceptual organization