Recent findings published in Hippocampus from the Cynthia Moss lab at Johns Hopkins University reveal that hippocampus neurons in bat respond to echolocation sound duration, but not to features that are typically associated with positioning and navigation. They performed multiple penetration acute recordings using high-density NeuroNexus Buzsaki16 probes to sample ensembles of neurons simultaneously.
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This Journal of Neuroscience paper by Song and Xu et al. from Dr. Ileana Hanganu-Opatz’s lab presents electrophysiology and optogenetics results using NeuroNexus multi-shank, multi-fiber optoelectrodes (A4x4-5mm-100-125-703-OA16LP). The lateral coverage from multiple shanks positioned recording sites in both layers 2/3 and 5/6 of developing mouse (ages P8-10 and P20-24) prefrontal cortex (PFC). They tested excitation and connectivity between PFC and hippocampus (CA1) in a model of mental disorder.
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Nikolas Karalis and Anton Sirota’s publication in Nature Communications uses NeuroNexus standard 16-shank probes (A16x1-2mm-50-177) in prefrontal cortex plus custom designed polytrodes (A1x64-Poly2-6mm-23s-160) in both prefrontal cortex and hippocampus of behaving mice. They recorded single units and measured LFPs both for current source density (CSD) analysis, and to study the oscillations coupled to breathing. Control recordings were done during optogenetically induced ripples. Read more about their results.
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