Closed-loop automated reaching apparatus (CLARA) for interrogating complex motor behaviors

Cristin Welle’s lab recently published their new system for integrating chronic, extracellular electrophysiology using NeuroNexus A1x16-3mm-100-177-CM16LP probes with video data to conduct closed-loop stimulation experiments. The linear array was implanted in the mouse motor cortex and captured spike data from all layers during freely moving reach behaviors. These recordings provided neural data to complement behavioral data such that reach-related activity could be extracted.