Effect of brain metastasis on ephys activity

Alberto Sanchez-Aguilera and Mariam Masmudi-Martin et al. with the Liset Menendez de la Prida and Manuel Valiente labs have published in Cancer Cell. NeuroNexus A1x16-5mm-100-413-A16 silicon probes were used for repeated, simultaneous acute recordings in cortex and hippocampus of mouse models of brain metastasis. Detection of sharp-wave ripples and theta oscillations enabled localization of the probe in the CA1 target. Measurement of LFPs in both areas was used to identify neural activity patterns that could help predict the presence and type of metastasis in the brain.