fMRI overconnectivity from cortical inactivation

A collaboration between the labs of Stefano Panzeri and Alessandro Gozzi published in Nature Communications. Multiple single-shank NeuroNexus probes (A1x16-5mm-50-703-A16) were inserted simultaneously using the Multi-Probe Manipulator to measure electrophysiological coherence as suggested by resting state fMRI scans. Four-shank probes (A4x8-5mm-200-400-703-A32) were inserted to span midline and target medial prefrontal cortex (PFC) in both hemispheres of the mouse. Their results reveal causes of increased fMRI connectivity.