Hippocampal changes in autism phenotypes

NeuroNexus chronic, 32-channel silicon probes were implanted chronically in behaving adult mice expressing autism-spectrum phenotypes. Paterno et al. from Scott Baraban’s lab at UCSF utilized A4x8-5mm-200-400-703-CM32 probes to record hippocampal LFPs and specifically gamma oscillations. They also used hippocampal sharp-wave ripples (SWR) and dentate spikes to localize the probe. Final probe location was determined with DiI, which was applied before implant. See more of their surgical methods and translational results in Cell Reports.

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