Hippocampal rhythms gate tFUS responses

Nguyen et al. and Jacek Dmochowski’s lab at City College of New York recorded local field potentials and multi-unit activity with NeuroNexus A1x32-15mm-100-177-A32 probes. They inserted probes with an angle to target adult rat hippocampal CA1, CA3 and dentate gyrus simultaneously and recorded during transcranial focused ultrasound stimulation (tFUS). Their results published in Brain Stimulation demonstrate that response to tFUS depends on pre-stimulation oscillations and sharp-wave ripples, SWRs.

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