Motor cortex inputs driving new dendritic spine dynamics
In their Science Advances publication, Sohn et al. from Yoshiyuki Kubota’s group at the National Institute for Physiological Sciences (NIPS) in Japan and Matthew Larkum’s group at Charité in Berlin used NeuroNexus acute, 16-channel probes (A1x16-5mm-100-177-A16) to record M1 neurons during optogenetic inactivation of M2 in C57BL/6J mice. Electrode sites spanned 100µm to 1600µm below the pial surface. Their study characterizes two presynaptic connections involved in pyramidal neuron spine dynamics during motor learning. Transient spines appear and disappear at corticocortical connections, while new and enlarging spines appear at thalamocortical connections.
Related Topics
Intern Spotlight: A Transformative Journey in Neurotechnology
We are thrilled to share the incredible …
Read publication
Exploring Auditory Neuroscience at the Biennial Woods Hole Summer School: A Deep Dive into the Biology of the Inner Ear
Every two years, some of the brightest m…
Read publication
7 Years Later: Revolutionizing Neural Research with SiC
NeuroNexus is committed to continuous im…
Read publication
A brief history of electrode technology
Our history of microelectrode technology…
Read publication