Silicon probes for monitoring EMG

NeuroNexus A1x32-6mm-50-177-H32_21mm probes were chronically implanted in the CA1 and dentate gyrus of freely behaving mice for LFP recordings. Through methods published in Cell Reports by Hisayuki Osanai et al. with the Takashi Kitamura lab at University of Texas Southwestern Medical Center, Independent Components Analysis of the LFP signals was used to isolate the EMG-related “noise” from the electrophysiology. The authors found that this IC-EMG is consistent with direct EMG recording when measuring relevant sleep and behavior states. Their findings demonstrate that silicon probe implants can also provide valuable EMG information without extra electrodes.

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