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September Newsletter

Back to School Sale – Ending September 19th

This is a great chance to get premium research tools at a discounted price – reply directly to this email, reach out to your NeuroNexus representative, or contact us here to inquire.

  • 20% off A-Stock probes

  • 30% off already discounted B-Stock probes

Browse the inventory here: https://shopping.neuronexus.com/Web-Store/Outlet-Store

Science Updates

Want to see how other researchers are using NeuroNexus products?

Did you know that if you navigate to any product on our website, you can view publications using that product with the Bioz plug-in? Give it a try by following this link → https://www.neuronexus.com/products/

Once you select a product, scrolling to the lower portion of the page will show you a list of publications – making it easy to explore how other scientists are using NeuroNexus arrays, systems, and software in real-world research. Explore Bioz

Predictive modeling of hemodynamics during viscerosensory neurostimulation vie neural computation mechanism in the brainstem

Lee et al., 2025, npj Digit.

The team explored how the brainstem’s nucleus tractus solitarius (NTS) translates sensory stimulation into changes in blood pressure and heart rate. They found that groups of NTS neurons follow clear activity patterns that can be used to predict cardiovascular responses. They used a NNx A1x16-Poly2 silicon probe. Read the study here

The dorsal and ventral hippocampus contribute differentially to spatial working memory and spatial coding in the prefrontal cortex

Babl et al., 2025, PLOS Biology

Researchers investigated how the dorsal and ventral hippocampus differentially contribute to spatial working memory and shape spatial coding in the prefrontal cortex. They did this using the NNx dDrive-m microdrive and NNx silicon probes (A1X16-5 mm-25–177-H16_21). Read the study here

Employee Spotlight: Engineering Tech Russ Monk!

This month we’re featuring Russ Monk, our awesome Engineering Tech. We’ve been lucky enough to have his expertise on the NeuroNexus team for 16 years!

Here at NeuroNexus, Russ is responsible for engineering all of the new designs and updates for PCBs, mounting IC chips on Smart Probes and Headstages, as well as assembling and testing the Smartbox Pro and Activus units. When asked about his favorite part of the job, he replied “the people I work with. I also hope we can help with understanding the brain better and the diseases that unfortunately are hinderances to people in everyday life”. 

Outside of work, Russ enjoys camping – “we have done the progression of starting out in small campers to now being considered ‘Glampers'”, he says. He’s visited many beautiful places in Michigan and across the US (fun fact – he’s swam in all 5 Great Lakes!) He cites some of his favorite movies to be comedies; Animal House, Caddyshack and We’re the Millers. “On a more serious note,” he says, “Shawshank Redemption”.

We’re grateful to Russ for his 16 years of expertise, dedication, and humor – and we’re proud to have him as part of the NeuroNexus family.

Coming soon…

For more than 20 years, NeuroNexus has been the leader in developing novel solutions for unique research requirements. With decades of collective experience, our team is always working to expand our product portfolio.

As SfN 2025 approaches, we’re excited to share the innovations we’ve been working on this year. Join us in San Diego to see our newest products and collaborations firsthand – and book time with our team now to explore how NeuroNexus can help take your science further.

 

August Newsletter

Welcome to the August edition of the NeuroNexus newsletter! Here’s what’s new and noteworthy this month:

Science Updates

Want to see how other researchers are using NeuroNexus products?

Did you know that if you navigate to any product on our website, you can view publications using that product with the Bioz plug-in? Give it a try by following this link → https://www.neuronexus.com/products/

Once you select a product, scrolling to the lower portion of the page will show you a list of publications – making it easy to explore how other scientists are using NeuroNexus arrays, systems, and software in real-world research.

Brain sources composing irregular field potentials have unique temporal signatures – Oscar Herreras, corresponding author

The team used NeuroNexus linear silicon probes with 16 or 32 recording sites to record high-resolution field potentials across multiple brain regions in anesthetized rats.

Read the study here

The neural circuit mechanism for auditory responses in the mediodorsal thalamic nucleus of awake mice –Ling Qin, corresponding author

Using NeuroNexus 16-channel probes (A1x16-3.8mm-50-177), the team identified phasic and sustained auditory responses shaped by brainstem and cortical inputs.

Read the study here

Late emergence of pathological oscillatory activity in the retina of the Retinitis pigmentosa model RCS (Royal College of Surgeons) rat – Frank Müller, corresponding author

With NeuroNexus adapters enabling intraretinal recordings from flexible Kiragami probes, researchers detected that retinal oscillations may interfere with retinal prostheses.

Read the study here

NeuroNexus Radiens Software Tutorials: Recording Settings

We’re launching a new video series to help you get the most out of Radiens. In each tutorial, we’ll walk through key features, tips, and workflows to accelerate your analysis.

This week’s video walks through the various recording settings in Allego. A variety of recording settings, all of which can be used alongside one another, allow you to meet your specific experimental needs. Watch the video here.

Employee spotlight: Andrea Worden

 

 

Meet Andrea Worden, our dedicated Senior Lab Tech who has been an essential part of the NeuroNexus team for an impressive 12 years. Andrea plays a key role in the development and assembly of both Optoelectrodes and traditional neural probes – work that Andrea says is “challenging at times, but also rewarding”.

Outside the lab, Andrea enjoys spending quality time with family and friends, and finds joy in walks along the Falling Waters Trail. Her favorite movie is “50 First Dates”, and her warm spirit brings positivity to every project she touches. We’re lucky to have Andrea’s experience and energy on the team!

July Newsletter

As July is wrapping up, here’s a look at what’s happening at NeuroNexus:

NeuroNexus Radiens Software Tutorials: Multiple Monitor View

We’re launching a new video series to help you get the most out of Radiens. In each tutorial, we’ll walk through key features, tips, and workflows to accelerate your analysis.

This video demonstrates how to view the same data in different ways using separate Monitor tabs, for example viewing spikes and LFPs simultaneously. Click here or click the thumbnail below to watch.

 

Science Updates

Check out some of these publications featuring NeuroNexus products!

Deciphering Auditory Hyperexcitability in Otgyl Mutant Mice Unravels an Auditory Neuropathy Mechanism 

Nicolas Michalski, corresponding author

Using NeuroNexus laminar probes, researchers recorded brain activity in Otogl mutant mice and identified a breakdown in how low-SR neurons process loud sounds. Read more

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Goal-specific hippocampal inhibition gates learning 

Annabelle C. Singer, corresponding author

The team used NeuroNexus Poly5 two-shank 64-channel silicone probes and matching 64-channel optoelectrodes, enabling high-density recording and optogenetic control of hippocampal ensembles during learning tasks. Read more

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Dexamethasone-loaded platelet-inspired nanoparticles improve intracortical microelectrode recording performance

Andrew Shoffstall, corresponding author – preprint

Using a NeuroNexus 16-channel single-shank intracortical microelectrode researchers demonstrated that dexamethasone-loaded nanoparticles significantly reduced inflammation, repaired the blood-brain barrier, and preserved neuron health, improving neural recording quality crucial for brain-machine interfaces. Read more

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Want to see how other researchers are using NeuroNexus products?

Looking for the right probe or configuration for your next experiment? Bioz makes it easy to explore how other scientists are using NeuroNexus arrays, systems, and software in real-world research. Explore Bioz here

June Newsletter

We hope you’ve had a great month of June! Here’s what’s happening at NeuroNexus:

NeuroNexus in Oslo for FENS

Last week, our own Dr. Rio Vetter traveled to Oslo, Norway for the FENS regional meeting to represent NeuroNexus. Thanks to everyone who stopped by our booth and chatted with us – it’s always great to connect with the neuroscience community.

 

 

 

 

 

 

 

 

 

 

Here’s how the Fusion Probe can change your research →

Are you limited by incomplete neural coverage? Fusion’s double-sided shank offers 360 degree coverage, capturing neural activity from all directions and providing an unbiased view of microcircuit dynamics with just one insertion.

Facing a complex setup? Fusion doubles the number of recording sites without requiring new hardware, headstones, or cables, streamlining your workflow effortlessly.

Concerned about efficient animal use in your experiments? Fusion provides richer, denser datasets per experiment, strengthening your statistical power while aligning with ethical standards (3Rs).

Struggling with compatibility issues in your existing workflows? Fusion integrates seamlessly into your current data analysis pipelines, supporting analyses from basic firing rates to advanced machine learning.

Learn more about the Fusion Probe here!

Science Updates

“Bacteria invade the brain following intracortical microelectrode implantation, inducing gut-brain axis disruption and contributing to reduced microelectrode performance”

Jeffrey R. Capadona, corresponding author 

 Utilizing NeuroNexus 16-channel single-shank silicon microelectrodes, the team detected microbial DNA sequences, including gut-related bacteria, at implant sites in mouse brains.

Read more

Whisking and locomotion are jointly represented in superior colliculus neurons 

Scott R. Pluta, corresponding author

Using a custom NeuroNexus 3-shank 128-channel silicon probe, researchers reveal how neurons in the mouse superior colliculus integrate whisker movement and running speed information.

Read more 

Want to see how other researchers are using NeuroNexus products? Bioz makes it easy to explore how other scientists are using NeuroNexus arrays, systems, and software in real-world research. Explore Bioz here. 

This month we’re featuring Andy Dwyer, our amazing senior assembly technician who has been with the NeuroNexus team for 14 years!

Is there a specific or product or service you specialize in here at NeuroNexus?

“Ddrives, Vectors, synapse probes and all high channel count probes.”

What is your favorite part of your job?

“Finding solutions to challenging problems.”

What is your favorite way to spend time outside of work?

“Hanging with my dog, ‘Fozzy.'”

What is your favorite book?

“‘Bad Chili’ by Joe R. Lansdale.”

Share a fun fact about you!

“I may have wire-bonded more devices than any single person on the planet.”

May Newsletter

As May wraps up, here’s a look at what’s happening at NeuroNexus:

The end of our Bundles offer is approaching – make sure you have the tools you need for your summer research.

  • Fast delivery, in-stock arrays
  • Complete, integrated solutions: Electrode Arrays, Data Acquisition Systems, Software and Accessories
  • Tailored systems + Bundle discounts

Contact us to see how we can build a system for you.

Science Updates

Check out some of these publications featuring NeuroNexus products!

Stereo olfaction underlies stable coding of head direction in blind mice

Using NeuroNexus Buz32 and Buz64 multi-shank silicon probes, they recorded head direction cells in the anterior dorsal thalamus.

Perceptual visual acuity declines with age in a rat model of retinitis pigmentosa while light perception is maintained

Using NeuroNexus A2x16-10mm-100-500-413-A32 silicon probes, researchers recorded from visual cortex, dLGN, and SC, mapping the degeneration of form vision and preservation of light response at the neural level.


Want to see how other researchers are using NeuroNexus products?


Looking for the right probe or configuration for your next experiment? Bioz makes it easy to explore how other scientists are using NeuroNexus arrays, systems, and software in real-world research.

Staff Spotlight

This month, we’re featuring the awesome Bill Willis! He’s been with NeuroNexus for 9 years this August, and we’re so grateful for his dedication and the energy he brings to the team every day.

Bill is a Michigan native who spent part of his 20s in California and grew up on Big Wolf Lake in Jackson, MI. He’s married to Linda, and their daughter Amanda recently turned 32. A fan of adventure, Bill enjoys downhill skiing across CO, CA, and MI, has ridden over 100 roller coasters around the country, and is preparing for his 13th cruise (to Alaska this August!). He’s also a proud Disney fan, former semi-professional clown (stage name Bolly), and a talented graphic designer whose work appears on brochures, Radiens software, and even a billboard on I-94. His favorite places include Sedonaand New York, and his playlists are full of classic rock and 80s pop. Bill says his favorite part of working at NeuroNexus is “being part of a team that builds innovative products and services making a global impact.”

 

Stay connected – follow us on social for tools, tips, and a peek inside the NeuroNexus community.

February Newsletter

We are excited to present our February 2025 Monthly Roundup, designed to keep you informed about the latest advancements, product releases, and insights from NeuroNexus. Here’s a glimpse of what this edition offers:

1. Science Updates – Discover recent publications featuring NeuroNexus products:

  • Striatal Interneuron Imbalance and Sensory Processing in a Rodent Autism Model

  • Precise 3D Localization of Intracerebral Implants Using a Simple Brain Clearing Method

  • An Independent Coding Scheme for Distance versus Position in the Hippocampus

2. Product Spotlight: XDAQ Gen 2- Introducing the next generation in electrophysiology research:

  • XDAQ One+
    Offering unparalleled input-output flexibility, the XDAQ One+ supports 512 or 1024 recording channels and 64 or 128 channels of stimulation. It can drive up to four Neuropixels probes in a single, portable unit.

  • XDAQ Core2
    This versatile entry-level ephys hub supports high-quality recording up to 512 channels and electrical stimulation configurable to 16 or 32 channels. The enhanced version offers built-in support for Neuropixels right out of the box.

3. The Neuroscience of Valentine’s Day – In the spirit of Valentine’s Day, explore the fascinating science behind falling in love, from brain chemistry to emotional connections. This video delves into what really happens in your brain when love takes over.

4. Staff Spotlight: Dillon Kipke – Meet Dillon Kipke, a software engineer lead who has been with NeuroNexus for six years!

For more details and to access the full newsletter, click here.

To subscribe to the monthly newsletter, click here!

Stay tuned for more updates and innovations from NeuroNexus!

Your Monthly Roundup from NeuroNexus

Intern Spotlight: A Transformative Journey in Neurotechnology

We are thrilled to share the incredible journey of Baptiste Tankwa, who recently completed his Leadership-In-Action (LIA) internship with us. Over the course of just two months, Baptiste immersed himself in the challenges and opportunities of developing innovative neural implants to address neurodegenerative diseases.

🔬 A Dive into Neurotechnology
From designing new neural implant concepts to engaging with multidisciplinary teams, Baptiste showcased exceptional dedication. He collaborated with leading professors, engineers, and technicians to understand the profound potential of translating technology from the lab to the market.

🤝 Challenges & Growth
Baptiste navigated cultural and professional challenges with remarkable adaptability. From adjusting to a fast-paced American work culture to mastering communication with diverse stakeholders, his experience epitomizes resilience and passion for innovation.

🚀 Looking Ahead
As Baptiste embarks on his next chapter in the Neuro-X master’s program at EPFL, we are confident he will continue pushing the boundaries of medical solutions for neurodegenerative diseases. His vision to bridge the gap between research and patient care inspires us all.

Thank you, Baptiste, for your hard work and dedication. We are proud to have been a part of your journey and can’t wait to see what you achieve next!

NeuroNexus Engineering Team

Read Baptiste’s report here!

Exploring Auditory Neuroscience at the Biennial Woods Hole Summer School: A Deep Dive into the Biology of the Inner Ear

Every two years, some of the brightest minds in auditory neuroscience gather at the Marine Biological Laboratory (MBL) in Woods Hole for an immersive, three-week course titled Biology of the Inner Ear (BIE). Since its inception in 2007, the course has offered graduate students and postdoctoral researchers from diverse scientific backgrounds—ranging from audiology to molecular biology and in vitro physiology—the opportunity to deepen their knowledge of auditory neuroscience through a combination of lectures, hands-on labs, and close interaction with world-renowned faculty​.

Dr. Peter Bremen led the course’s participants through an engaging and practical demonstration of in-vivo extracellular neurophysiology using the Mongolian gerbil. This portion of the course allowed students to conduct recordings from the inferior colliculus and auditory cortex while exposing the gerbils to auditory stimuli. “They obtained frequency tuning, level tuning, and amplitude-modulation tuning curves,” Dr. Bremen explained. “It was an excellent opportunity for them to learn about hardware components like pre-amps and AD converters, as well as stimulus generation, spike sorting, and data analysis.”

For many students, this was their first introduction to in-vivo neurophysiology. According to Dr. Bremen, the experience generated enthusiasm and many insightful questions from the students. “The students were very engaged, not only with the scientific aspects but also with the technical components of the rig setup, including the electrodes, hardware, and software,” he shared.

The Role of NeuroNexus in Supporting Advanced Research

NeuroNexus, a company known for its advanced neurophysiology tools, was instrumental in making this demonstration possible. Dr. Bremen, a long-time user of NeuroNexus products, emphasized their impact on his teaching and research. “I’ve used NeuroNexus electrodes for more than 10 years,” he shared. “Their recording quality is excellent, and the price is unbeatable. One of the things I particularly appreciate is the reusability of the electrodes without any loss in quality.”

For the 2024 course, NeuroNexus generously provided equipment, which allowed participants to gain hands-on experience with high-quality neurophysiology tools. “Without their support, the in-vivo demonstration wouldn’t have been possible,” Dr. Bremen noted. The use of NeuroNexus products not only enhanced the students’ technical skills but also provided them with insights into setting up and maintaining a fully functional electrophysiology rig.

A Collaborative Success

The Biology of the Inner Ear course is known for fostering close relationships between students and faculty, allowing for a collaborative learning environment. Reflecting on the success of the in-vivo demonstrations, Dr. Bremen was enthusiastic: “All in all, I think our demos were a great success and very informative for the students, many of whom had no prior experience with in-vivo neurophysiology.”

When asked if he would continue using NeuroNexus products in the future, Dr. Bremen’s response was emphatic: “Yes, definitely!”

The biennial Biology of the Inner Ear course continues to play a crucial role in training the next generation of auditory neuroscientists. Thanks to the collaboration between educators, researchers, and supporters like NeuroNexus, participants are gaining the skills and knowledge needed to make significant advancements in auditory science​.

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