This paper from Levelt’s group explores the critical role of astrocyte cannabinoid receptor 1 (CB1) in the development and plasticity of the mouse visual cortex. Researchers demonstrated that the absence of CB1 receptors in astrocytes disrupts the maturation of inhibitory neurons and diminishes ocular dominance plasticity, which reflects the brain’s ability to adapt to changes in visual input.
To achieve these findings, Neuronexus products (A1x16-5mm-25-177-A16) were used for precise neural recordings, enabling high-resolution monitoring of cortical activity. These tools provided crucial data on neural dynamics and plasticity changes in the visual cortex, helping to establish a clear link between astrocyte CB1 receptor function and inhibitory neuron development.
