Join us on February 19th at 11am ET for the first of a new webinar series where we’ll be showcasing real science using NeuroNexus products. In the first session of our webinar series, this Science Showcase will highlight researchers using Allego, the acquisition application in Radiens Suite, to explore fundamental questions in neural recording and analysis. Speakers will share how they design experiments, acquire high-quality neural data, and leverage real-time analytics and visualization to interrogate neural dynamics and broader biological hypotheses. Through these talks, you’ll see how integrated data acquisition and digital modeling tools in Allego support deeper scientific insight. Register here to save your spot!
Additionally, we’re looking for more researchers to share their experience with Allego. If you’re interested in having your research showcased,please submit below and we’ll be in touch!
Help us welcome Dr. Rosie Rae to the NNx team. Rosie is a tenacious, positive, and driven scientist with expertise in neurophysiology and data analysis. As an Application Scientist, she is passionate about rigorous, ethical science and committed to making complex research accessible and understandable for all audiences. Connect with Rosie here!
As the data aqcisition application within Radiens Suite, Allego provides DAQ hardware control with real-time analytics and visualization of both neural recordings and an innovative digital twin model of the neural interface.
Latest Version of Allego
Coming Soon: Tiered Software Update Channels
We are introducing tiered release channels for Allego, allowing users to select the update cadence and feature set that best aligns with their workflows and validation requirements.
Learn more about the Radiens Software Suite
In this study, the team investigated the microglial inflammatory response to cortical electrode implantation – an important consideration, as these inflammatory cascades can impair the performance of intracortical brain-computer interfaces and intracranial electrophysiological recordings. They found that low-intensity pulsed ultrasound stimulation increased microglial migration speed, promoted microglial expansion, and reduced microglial activation, all of which point to improved tissue healing and surveillance. Additionally, ultrasound stimulation reduced microglial coverage of the electrode and limited astrocytic scarring, resulting in improved recording performance over time. Together, these findings suggest that low-intensity pulsed ultrasound can mitigate the foreign body response surrounding chronic intracortical microelectrodes and can yield better recording quality.
This study used a combination of NNx equipment including a passive single shank 16 channel microelectrode (A1x16) and an active four shank 16 channel microelectrode (A4x4), which were attached to a NNx headstage. All experimentation was recorded with a SmartBox Pro running Allego the acquisition application within NNx Radiens software.
