Deconstructing the neural circuit underlying social hierarchy in mice

Congratulations to Hailan Hu and their colleagues from Zhejiang University for their publication, “Deconstructing the neural circuit underlying social hierarchy in mice”. They investigated how the dorsomedial prefrontal cortex (dmPFC) regulates social dominance. Using high-density Neuronexus silicon probes, the team recorded in-vivo neural activity to identify two antagonistic dmPFC pathways: one promoting winning behaviors (projecting to the dorsal raphe nucleus) and the other driving losing behaviors (projecting to the basolateral amygdala).