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Science Updates

Information flow in the rat thalamo-cortical system: spontaneous vs. stimulus-evoked activities

Hirokazo Takahashi’s lab used a NeuroNexus probe to simultaneously target the auditory cortex and thalamus of rats. Their published results in Nature Scientific Reports demonstrate that information flow was dynamic depending on the stimulus processing mode and that thalamo-cortical communication was strengthened during stimulus presentation, while disappeared during spontaneous activity.

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Information flow in the rat thalamo-cortical system: spontaneous vs. stimulus-evoked activities
Science Updates

Spatial modulation of dark versus bright stimulus responses in the mouse visual system

Bilal Haider’s lab at Georgia Tech used NeuroNexus 32-channel probes with linear and poly3 layouts to record neural activity across layers of V1 and LGN, respectively, in head-fixed stationary mice. Their results showed that OFF responses dominated in the central visual field, whereas ON and OFF responses were more balanced in the periphery. These findings were consistent across LFP, spikes, and subthreshold membrane potential in V1, and were aligned with spatial biases in ON and OFF responses in LGN.

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Spatial modulation of dark versus bright stimulus responses in the mouse visual system
Science Updates

Near-infrared manipulation of multiple neuronal populations via trichromatic upconversion

Liu at.al published their results in Nature Communications using NeuroNexus A4x8-5mm microelectrode arrays. Single neuron recordings were captured during optogenetic stimulation with blue, green and red light emitted by trichromatic upcoversion nanoparticles with excitation-specific luminescence. They showed the separation of blue, green, and red color emissions by measuring the spike activity of multiple neuronal populations under selective activation with different wavelengths of near infrared light.

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Near-infrared manipulation of multiple neuronal populations via trichromatic upconversion