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NeuroNexus · neuronexus.com · Glossary

A-Series Probes (Polytrode & Tetrode)

Hardware
A polytrode or tetrode silicon probe has closely spaced sets of sites arranged in several columns or in clusters of four along the shank, so a neuron is recorded on several sites at once for single-unit isolation and current-source density analysis.

Polytrode designs place sites in columns along the shank, so the dense sampling still covers depth. Tetrode designs group sites in fours at intervals along the shank, giving isolation at each cluster and no sites between them. Catalog designs have 16 to 256 sites on 1 to 9 shanks, 3 to 10 mm long, with sites usually 177 µm² and 160 and 121 µm² options, at a within-cluster pitch of about 20 to 25 µm; iridium is the standard site metal, with Z-Coat (PEDOT) as an option. The Q-Trode series is the single-tetrode version; spike sorting and current-source density are the analyses the layouts serve.

Records and stimulates. Research use only.

Typical values

Catalog designs39
Sites16 to 256
Shanks1 to 9
Shank length3 to 10 mm
Site area97 to 220 µm²
Cluster pitchabout 20 to 25 µm

References

  1. Buzsáki, 2004 — Large-scale recording of neuronal ensembles. Nat Neurosci 7(5), 446–451

Related Terms

Silicon ProbeA-Series Probes (Linear and Edge Layouts)A-Series Probes (Buzsaki)Q-Trode Series Silicon ProbesSpike SortingSite Pitch (Across)Probe Geometry and Site LayoutsNeuropixels Probe

Cite this term

NeuroNexus. "A-Series Probes (Polytrode & Tetrode)." NeuroNexus Glossary, updated 2026-10-31. https://www.neuronexus.com/resources/glossary/a-series-polytrode-tetrode

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