NeuroNexus has partnered with Corticale to help make this advanced probe technology available to researchers around the world. SiNAPS products utilize a new probe technology with active CMOS circuitry integrated onto the probe. SiNAPS technology is an innovative advancement in multi-electrode solutions for in vivo electrophysiological studies on central and peripheral nervous system. This technology implements the Active Pixel Sensor (APS) concept in which active circuits for signal amplification, low-pass filtering, and multiplexing read-out are located directly underneath each electrode-pixel. To access NeuroNexus' existing design catalog for 64-, 128- and 256-channel Activus probes, check out Activus-NNx.

• High number of electrode sites
• High-density electrode spacing
• Large, high-resolution span of electrodes
• Ability to record from all electrode sites, not just a subset like the neuropixel probes
• Improved signal-to-noise (SNR) of acquired signals
• Ultra-compact package
• Multiplexed signals (32:1), reduced connector size

• Low noise: 7.5 μVRMS (300-7500 Hz)
• In-pixel amplifier: 46dB (DC-4kHz)
• Low power: 6μW/pixel
• Sampling frequency: 25ksample/s
• Electrode size: 15x15 μm²
• Electrode pitch: 29 μm
• Shank spacing: 560 μm
• Electrode material: Platinum

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• Smartbox Pro
• Activus SiNAPS interface box
• Laptop or desktop computer
• Radiens neuro-analytics suite

• An implantable active pixel sensor CMOS-probe for simultaneous large-scale neural recordings. Angotzi GA, et al., Biosensors & bioelectronics 126 (2019): 355-364.

• Multi-shanks SiNAPs active pixel sensor CMOS probe: 1024 simultaneously recording channels for high-density intracortical brain mapping. Boi F., et al., bioRxiv (2019): 749911.